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SINE (selective inhibitor of nuclear export) – translational science in a new class of anti-cancer agents
Regulation of protein trafficking between the nucleus and cytoplasm represents a novel control point for antineoplastic intervention. Several proteins involved with cellular growth and survival depend on precise and timely positioning within the cell to fulfill their functions, and the nuclear membr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197302/ https://www.ncbi.nlm.nih.gov/pubmed/25281264 http://dx.doi.org/10.1186/s13045-014-0067-3 |