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Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma

BACKGROUND: Endometrial cancer is the most common gynecologic malignancy. Type II endometrial carcinoma is often poorly differentiated and patients diagnosed with Type II disease (~11%) are disproportionately represented in annual endometrial cancer deaths (48%). Recent genomic studies highlight mut...

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Detalles Bibliográficos
Autores principales: Theisen, Emily R, Gajiwala, Snehal, Bearss, Jared, Sorna, Venkataswamy, Sharma, Sunil, Janat-Amsbury, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197342/
https://www.ncbi.nlm.nih.gov/pubmed/25300887
http://dx.doi.org/10.1186/1471-2407-14-752