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Peptide Scrambling During Collision-Induced Dissociation is Influenced by N-terminal Residue Basicity

‘Bottom up’ proteomic studies typically use tandem mass spectrometry data to infer peptide ion sequence, enabling identification of the protein whence they derive. The majority of such studies employ collision-induced dissociation (CID) to induce fragmentation of the peptide structure giving diagnos...

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Detalles Bibliográficos
Autores principales: Chawner, Ross, Holman, Stephen W., Gaskell, Simon J., Eyers, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197365/
https://www.ncbi.nlm.nih.gov/pubmed/25135610
http://dx.doi.org/10.1007/s13361-014-0968-y