Dissolution Testing of Hardly Soluble Materials by Surface Sensitive Techniques: Clotrimazole from an Insoluble Matrix

PURPOSE: The low aqueous solubility of many drugs impedes detailed investigation as the detection limit of standard testing routines is limited. This is further complicated within application relevant thin films typical used in patches or stripes for buccal or topical routes. METHODS: In this work a...

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Detalles Bibliográficos
Autores principales: Ehmann, Heike M. A., Winter, Sascha, Griesser, Thomas, Keimel, Roman, Schrank, Simone, Zimmer, Andreas, Werzer, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197366/
https://www.ncbi.nlm.nih.gov/pubmed/24752480
http://dx.doi.org/10.1007/s11095-014-1368-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197366/
https://www.ncbi.nlm.nih.gov/pubmed/24752480
http://dx.doi.org/10.1007/s11095-014-1368-5

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