Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

During development, tissue repair, and tumor growth, most blood vessel networks are generated through angiogenesis. Vascular endothelial growth factor (VEGF) is a key regulator of this process and currently both VEGF and its receptors, VEGFR1, VEGFR2, and Neuropilin1 (NRP1), are targeted in therapeu...

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Detalles Bibliográficos
Autores principales: Gelfand, Maria V, Hagan, Nellwyn, Tata, Aleksandra, Oh, Won-Jong, Lacoste, Baptiste, Kang, Kyu-Tae, Kopycinska, Justyna, Bischoff, Joyce, Wang, Jia-Huai, Gu, Chenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197402/
https://www.ncbi.nlm.nih.gov/pubmed/25244320
http://dx.doi.org/10.7554/eLife.03720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197402/
https://www.ncbi.nlm.nih.gov/pubmed/25244320
http://dx.doi.org/10.7554/eLife.03720

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