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Self-assembling choline mimicks with enhanced binding affinities to C-LytA protein

Streptococcus pneumoniae (pneumococcus) causes multiple illnesses in humans. Exploration of effective inhibitors with multivalent attachment sites for choline-binding modules is of great importance to reduce the pneumococcal virulence. In this work, we successfully developed two self-assembling chol...

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Detalles Bibliográficos
Autores principales: Shi, Yang, Zhou, Hao, Zhang, Xiaoli, Wang, Jingyu, Long, Jiafu, Yang, Zhimou, Ding, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197414/
https://www.ncbi.nlm.nih.gov/pubmed/25315737
http://dx.doi.org/10.1038/srep06621