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Phosphoinositide 3-kinase p85beta regulates invadopodium formation

The acquisition of invasiveness is characteristic of tumor progression. Numerous genetic changes are associated with metastasis, but the mechanism by which a cell becomes invasive remains unclear. Expression of p85β, a regulatory subunit of phosphoinositide-3-kinase, markedly increases in advanced c...

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Detalles Bibliográficos
Autores principales: Cariaga-Martínez, Ariel E., Cortés, Isabel, García, Esther, Pérez-García, Vicente, Pajares, María J., Idoate, Miguel A., Redondo-Muñóz, Javier, Antón, Inés M., Carrera, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197441/
https://www.ncbi.nlm.nih.gov/pubmed/25217619
http://dx.doi.org/10.1242/bio.20148185