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Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers

Autocrine activation of the Wnt/β-catenin pathway occurs in several cancers, notably in breast tumors, and is associated with higher expression of various Wnt ligands. Using various inhibitors of the FZD/LRP receptor complex, we demonstrate that some adenosquamous carcinomas that develop in MMTV-CUX...

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Detalles Bibliográficos
Autores principales: Vadnais, Charles, Shooshtarizadeh, Peiman, Rajadurai, Charles V., Lesurf, Robert, Hulea, Laura, Davoudi, Sayeh, Cadieux, Chantal, Hallett, Michael, Park, Morag, Nepveu, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197442/
https://www.ncbi.nlm.nih.gov/pubmed/25217618
http://dx.doi.org/10.1242/bio.20148193