Cargando…

Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers

Autocrine activation of the Wnt/β-catenin pathway occurs in several cancers, notably in breast tumors, and is associated with higher expression of various Wnt ligands. Using various inhibitors of the FZD/LRP receptor complex, we demonstrate that some adenosquamous carcinomas that develop in MMTV-CUX...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vadnais, Charles, Shooshtarizadeh, Peiman, Rajadurai, Charles V., Lesurf, Robert, Hulea, Laura, Davoudi, Sayeh, Cadieux, Chantal, Hallett, Michael, Park, Morag, Nepveu, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197442/ https://www.ncbi.nlm.nih.gov/pubmed/25217618 http://dx.doi.org/10.1242/bio.20148193

Ejemplares similares

RAS Transformation Requires CUX1-Dependent Repair of Oxidative DNA Damage
por: Ramdzan, Zubaidah M., et al.
Publicado: (2014)

Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice
por: Siam, Rania, et al.
Publicado: (2009)

CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage
por: Vadnais, Charles, et al.
Publicado: (2012)

The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts
por: Ramdzan, Zubaidah M., et al.
Publicado: (2015)

Long-range transcriptional regulation by the p110 CUX1 homeodomain protein on the ENCODE array
por: Vadnais, Charles, et al.
Publicado: (2013)

Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes
por: Harada, Ryoko, et al.
Publicado: (2008)

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes
por: Shooshtarizadeh, Peiman, et al.
Publicado: (2019)

Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes
por: Beauchemin, Hugues, et al.
Publicado: (2017)

The DNA repair function of CUX1 contributes to radioresistance
por: Ramdzan, Zubaidah M., et al.
Publicado: (2017)

CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma
por: Feng, Fan, et al.
Publicado: (2021)

Effect of CUX1 on the Proliferation of Hu Sheep Dermal Papilla Cells and on the Wnt/β-Catenin Signaling Pathway
por: Zhou, Hui, et al.
Publicado: (2023)

Inactivating CUX1 mutations promote tumorigenesis
por: Wong, Chi C., et al.
Publicado: (2013)

Overexpressed P75CUX1 promotes EMT in glioma infiltration by activating β-catenin
por: Xu, Anqi, et al.
Publicado: (2021)

CUX1, A Controversial Player in Tumor Development
por: Liu, Ning, et al.
Publicado: (2020)

Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1)
por: Beak, Ju Youn, et al.
Publicado: (2008)

Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells
por: Gaudreau, Marie-Claude, et al.
Publicado: (2016)

Telomeres are elongated in older individuals in a hibernating rodent, the edible dormouse (Glis glis)
por: Hoelzl, Franz, et al.
Publicado: (2016)

Fatty Acid Composition of M. Biceps Femoris of Edible Dormouse (Glis glis L.)
por: Pađen, Lana, et al.
Publicado: (2022)

The role of CUX1 in antagonizing NF-κB signaling in TAMs
por: Kühnemuth, Benjamin, et al.
Publicado: (2014)

Genomic studies controvert the existence of the CUX1 p75 isoform
por: Krishnan, Manisha, et al.
Publicado: (2022)

Telomere dynamics in free-living edible dormice (Glis glis): the impact of hibernation and food supply
por: Hoelzl, Franz, et al.
Publicado: (2016)

The Transcription Factor Cux1 Regulates Dendritic Morphology of Cortical Pyramidal Neurons
por: Li, Ning, et al.
Publicado: (2010)

CUX1—Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors
por: Krug, Sebastian, et al.
Publicado: (2020)

Edible dormice (Glis glis) avoid areas with a high density of their preferred food plant - the European beech
por: Cornils, Jessica S., et al.
Publicado: (2017)

Monitoring Campaign over an Edible Dormouse Population (Glis glis; Rodentia: Gliridae) in Sicily: First Report of Mesocestodiasis
por: Schirò, Giorgia, et al.
Publicado: (2021)

Role of GLIS3 in thyroid development and in the regulation of gene expression in thyroid specific Glis3KO mice
por: Kang, Hong Soon, et al.
Publicado: (2023)

CUX2 functions as an oncogene in papillary thyroid cancer
por: Sun, Yihan, et al.
Publicado: (2018)

The transcription factor CUX1 negatively regulates invasion in castrate resistant prostate cancer
por: Dorris, Emma R., et al.
Publicado: (2020)

How to spend the summer? Free-living dormice (Glis glis) can hibernate for 11 months in non-reproductive years
por: Hoelzl, Franz, et al.
Publicado: (2015)

Therapeutic targeting of circ‐CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression
por: Li, Huanhuan, et al.
Publicado: (2019)

Transcriptional regulation of Glis2 in hepatic fibrosis
por: Gong, Huan-Yu, et al.
Publicado: (2023)

Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival
por: Lufkin, Leon, et al.
Publicado: (2022)

CUX1-related neurodevelopmental disorder: deep insights into phenotype-genotype spectrum and underlying pathology
por: Oppermann, Henry, et al.
Publicado: (2023)

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma
por: Arensman, Michael D., et al.
Publicado: (2013)

Two novel Bartonella (sub)species isolated from edible dormice (Glis glis): hints of cultivation stress-induced genomic changes
por: Bartoš, Oldřich, et al.
Publicado: (2023)

Autocrine BMP4 Signaling Enhances Tumor Aggressiveness via Promoting Wnt/β-Catenin Signaling in IDH1-mutant Gliomas
por: Zhou, Yiqiang, et al.
Publicado: (2019)

Effects of downregulating GLIS1 transcript on preimplantation development and gene expression of bovine embryos
por: TAKAHASHI, Kazuki, et al.
Publicado: (2015)

GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans
por: Nair, K. Saidas, et al.
Publicado: (2021)

GLIS1 in Cancer-Associated Fibroblasts Regulates the Migration and Invasion of Ovarian Cancer Cells
por: Kim, Mi Joung, et al.
Publicado: (2022)

GLIS1, a potential candidate gene affect fat deposition in sheep tail
por: Luo, Rongsong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_50s4k3rh0vi1vcp2bomij5hqep