Stat3 signaling regulates embryonic stem cell fate in a dose-dependent manner

Stat3 is essential for mouse embryonic stem cell (mESC) self-renewal mediated by LIF/gp130 receptor signaling. Current understanding of Stat3-mediated ESC self-renewal mechanisms is very limited, and has heretofore been dominated by the view that Stat3 signaling functions in a binary “on/off” manner...

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Detalles Bibliográficos
Autores principales: Tai, Chih-I, Schulze, Eric N., Ying, Qi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197444/
https://www.ncbi.nlm.nih.gov/pubmed/25238758
http://dx.doi.org/10.1242/bio.20149514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197444/
https://www.ncbi.nlm.nih.gov/pubmed/25238758
http://dx.doi.org/10.1242/bio.20149514

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