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Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice

Gene therapies for neurological diseases with autonomic or gastrointestinal involvement may require global gene expression. Gastrointestinal complications are often associated with Parkinson's disease and autism. Lewy bodies, a pathological hallmark of Parkinson's brains, are routinely ide...

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Detalles Bibliográficos
Autores principales: Gombash, Sara E., Cowley, Christopher J., Fitzgerald, Julie A., Hall, Jodie C. E., Mueller, Christian, Christofi, Fedias L., Foust, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197761/
https://www.ncbi.nlm.nih.gov/pubmed/25360081
http://dx.doi.org/10.3389/fnmol.2014.00081