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AhR-Mediated, Non-Genomic Modulation of IDO1 Function

The evolutionary process has conferred a dual – enzymatic and signaling – function on the ancestral metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1), which has long been known for converting the essential amino acid tryptophan (TRP) into neuroactive and immunoactive catabolites (kynurenines). I...

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Detalles Bibliográficos
Autores principales: Pallotta, Maria Teresa, Fallarino, Francesca, Matino, Davide, Macchiarulo, Antonio, Orabona, Ciriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197771/
https://www.ncbi.nlm.nih.gov/pubmed/25360135
http://dx.doi.org/10.3389/fimmu.2014.00497