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Pin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction
The cell adhesion molecule Neuroligin2 (NL2) is localized selectively at GABAergic synapses, where it interacts with the scaffolding protein gephyrin in the post-synaptic density. However, the role of this interaction for formation and plasticity of GABAergic synapses is unclear. Here, we demonstrat...
Autores principales: | Antonelli, Roberta, Pizzarelli, Rocco, Pedroni, Andrea, Fritschy, Jean-Marc, Del Sal, Giannino, Cherubini, Enrico, Zacchi, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197815/ https://www.ncbi.nlm.nih.gov/pubmed/25297980 http://dx.doi.org/10.1038/ncomms6066 |
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