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Conserved microRNA editing in mammalian evolution, development and disease

BACKGROUND: Mammalian microRNAs (miRNAs) are sometimes subject to adenosine-to-inosine RNA editing, which can lead to dramatic changes in miRNA target specificity or expression levels. However, although a few miRNAs are known to be edited at identical positions in human and mouse, the evolution of m...

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Detalles Bibliográficos
Autores principales: Warnefors, Maria, Liechti, Angélica, Halbert, Jean, Valloton, Delphine, Kaessmann, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197820/
https://www.ncbi.nlm.nih.gov/pubmed/24964909
http://dx.doi.org/10.1186/gb-2014-15-6-r83