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IVT-seq reveals extreme bias in RNA sequencing
BACKGROUND: RNA-seq is a powerful technique for identifying and quantifying transcription and splicing events, both known and novel. However, given its recent development and the proliferation of library construction methods, understanding the bias it introduces is incomplete but critical to realizi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197826/ https://www.ncbi.nlm.nih.gov/pubmed/24981968 http://dx.doi.org/10.1186/gb-2014-15-6-r86 |