Murine Langerin(+) dermal dendritic cells prime CD8(+) T cells while Langerhans cells induce cross-tolerance

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Skin dendritic cells (DCs) control the immunogenicity of cutaneously administered vaccines. Antigens targeted to DCs via the C-type lectin Langerin/CD207 are cross-presented to CD8(+) T cells in vivo. We investigated the relative roles of Langerhans cells (LCs) and Langerin(+) dermal DCs (dDCs) in d...

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Detalles Bibliográficos
Autores principales: Flacher, Vincent, Tripp, Christoph H, Mairhofer, David G, Steinman, Ralph M, Stoitzner, Patrizia, Idoyaga, Juliana, Romani, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197865/
https://www.ncbi.nlm.nih.gov/pubmed/25085878
http://dx.doi.org/10.15252/emmm.201303283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197865/
https://www.ncbi.nlm.nih.gov/pubmed/25085878
http://dx.doi.org/10.15252/emmm.201303283

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