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Murine Langerin(+) dermal dendritic cells prime CD8(+) T cells while Langerhans cells induce cross-tolerance
Skin dendritic cells (DCs) control the immunogenicity of cutaneously administered vaccines. Antigens targeted to DCs via the C-type lectin Langerin/CD207 are cross-presented to CD8(+) T cells in vivo. We investigated the relative roles of Langerhans cells (LCs) and Langerin(+) dermal DCs (dDCs) in d...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197865/ https://www.ncbi.nlm.nih.gov/pubmed/25085878 http://dx.doi.org/10.15252/emmm.201303283 |
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por Flacher, Vincent, Tripp, Christoph H, Mairhofer, David G, Steinman, Ralph M, Stoitzner, Patrizia, Idoyaga, Juliana, Romani, Nikolaus
Publicado 2014
Enlace del recurso
Publicado 2014
Enlace del recurso
Online
Artículo
Texto