ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis

Elevated glycolysis is a common metabolic trait of cancer, but what drives such metabolic reprogramming remains incompletely clear. We report here a novel transcriptional repressor-mediated negative regulation of glycolysis. ZBTB7A, a member of the POK (POZ/BTB and Krüppel) transcription repressor f...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xue-Song, Haines, Jenna E., Mehanna, Elie K., Genet, Matthew D., Ben-Sahra, Issam, Asara, John M., Manning, Brendan D., Yuan, Zhi-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197949/
https://www.ncbi.nlm.nih.gov/pubmed/25184678
http://dx.doi.org/10.1101/gad.245910.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197949/
https://www.ncbi.nlm.nih.gov/pubmed/25184678
http://dx.doi.org/10.1101/gad.245910.114

Ejemplares similares