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Incomplete replication generates somatic DNA alterations within Drosophila polytene salivary gland cells
DNA replication remains unfinished in many Drosophila polyploid cells, which harbor disproportionately fewer copies of late-replicating chromosomal regions. By analyzing paired-end high-throughput sequence data from polytene larval salivary gland cells, we define 112 underreplicated (UR) euchromatic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197960/ https://www.ncbi.nlm.nih.gov/pubmed/25128500 http://dx.doi.org/10.1101/gad.245811.114 |