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Incomplete replication generates somatic DNA alterations within Drosophila polytene salivary gland cells

DNA replication remains unfinished in many Drosophila polyploid cells, which harbor disproportionately fewer copies of late-replicating chromosomal regions. By analyzing paired-end high-throughput sequence data from polytene larval salivary gland cells, we define 112 underreplicated (UR) euchromatic...

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Detalles Bibliográficos
Autores principales:	Yarosh, Will, Spradling, Allan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Resource/Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197960/ https://www.ncbi.nlm.nih.gov/pubmed/25128500 http://dx.doi.org/10.1101/gad.245811.114

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