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The FACT complex interacts with the E3 ubiquitin ligase Psh1 to prevent ectopic localization of CENP-A
Centromere identity and its epigenetic maintenance require the incorporation of a histone H3 variant called CENP-A at centromeres. CENP-A mislocalization to ectopic sites may disrupt chromatin-based processes and chromosome segregation, so it is important to uncover the mechanisms by which this vari...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197964/ https://www.ncbi.nlm.nih.gov/pubmed/25128498 http://dx.doi.org/10.1101/gad.243113.114 |