Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells

Tissues may adopt diverse strategies to establish specific transcriptional programs in daughter lineages. In intestinal crypts, enhancers for genes expressed in both major cell types appear broadly permissive in stem and specified progenitor cells. In blood, another self-renewing tissue, it is uncle...

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Detalles Bibliográficos
Autores principales: Luyten, Annouck, Zang, Chongzhi, Liu, X. Shirley, Shivdasani, Ramesh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Resource/Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197967/
https://www.ncbi.nlm.nih.gov/pubmed/25128499
http://dx.doi.org/10.1101/gad.240101.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197967/
https://www.ncbi.nlm.nih.gov/pubmed/25128499
http://dx.doi.org/10.1101/gad.240101.114

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