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Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells
Tissues may adopt diverse strategies to establish specific transcriptional programs in daughter lineages. In intestinal crypts, enhancers for genes expressed in both major cell types appear broadly permissive in stem and specified progenitor cells. In blood, another self-renewing tissue, it is uncle...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197967/ https://www.ncbi.nlm.nih.gov/pubmed/25128499 http://dx.doi.org/10.1101/gad.240101.114 |