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Go-6976 Reverses Hyperglycemia-Induced Insulin Resistance Independently of cPKC Inhibition in Adipocytes

Chronic hyperglycemia induces insulin resistance by mechanisms that are incompletely understood. One model of hyperglycemia-induced insulin resistance involves chronic preincubation of adipocytes in the presence of high glucose and low insulin concentrations. We have previously shown that the mTOR c...

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Detalles Bibliográficos
Autores principales: Robinson, Katherine A., Hegyi, Krisztina, Hannun, Yusuf A., Buse, Maria G., Sethi, Jaswinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198081/
https://www.ncbi.nlm.nih.gov/pubmed/25330241
http://dx.doi.org/10.1371/journal.pone.0108963