Cargando…

Go-6976 Reverses Hyperglycemia-Induced Insulin Resistance Independently of cPKC Inhibition in Adipocytes

Chronic hyperglycemia induces insulin resistance by mechanisms that are incompletely understood. One model of hyperglycemia-induced insulin resistance involves chronic preincubation of adipocytes in the presence of high glucose and low insulin concentrations. We have previously shown that the mTOR c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robinson, Katherine A., Hegyi, Krisztina, Hannun, Yusuf A., Buse, Maria G., Sethi, Jaswinder K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198081/ https://www.ncbi.nlm.nih.gov/pubmed/25330241 http://dx.doi.org/10.1371/journal.pone.0108963

Ejemplares similares

Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI
por: Hurtado, Erica, et al.
Publicado: (2017)

cPKC regulates interphase nuclear size during Xenopus development
por: Edens, Lisa J., et al.
Publicado: (2014)

Statin-specific inhibition of Rab-GTPase regulates cPKC-mediated IKs internalization
por: Ronzier, Elsa, et al.
Publicado: (2019)

Ameliorating effects of Gö6976, a pharmacological agent that inhibits protein kinase D, on collagen-induced arthritis
por: Yoon, Tae Won, et al.
Publicado: (2019)

Opposed Actions of PKA Isozymes (RI and RII) and PKC Isoforms (cPKCβI and nPKCε) in Neuromuscular Developmental Synapse Elimination
por: Garcia, Neus, et al.
Publicado: (2019)

Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1
por: Merzoug-Larabi, Messaouda, et al.
Publicado: (2017)

cPKCγ membrane translocation is involved in herkinorin-induced neuroprotection against cerebral ischemia/reperfusion injury in mice
por: Gui, Xiaochen, et al.
Publicado: (2017)

Clematichinenoside Serves as a Neuroprotective Agent Against Ischemic Stroke: The Synergistic Action of ERK1/2 and cPKC Pathways
por: Liu, Chao, et al.
Publicado: (2016)

Monocular Deprivation Affects Visual Cortex Plasticity Through cPKCγ-Modulated GluR1 Phosphorylation in Mice
por: Zhang, Yunxia, et al.
Publicado: (2020)

Molecular mechanisms of hydrogen sulfide against uremic accelerated atherosclerosis through cPKCβII/Akt signal pathway
por: Xiong, Ruifang, et al.
Publicado: (2019)

cPKCγ-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/Reperfusion
por: Hua, Rongrong, et al.
Publicado: (2018)

Effect of the cPKCγ-Ng Signaling System on Rapid Eye Movement Sleep Deprivation-Induced Learning and Memory Impairment in Rats
por: Xu, Shu, et al.
Publicado: (2021)

Retraction: Clematichinenoside Serves as a Neuroprotective Agent Against Ischemic Stroke: The Synergistic Action of ERK1/2 and cPKC Pathways
Publicado: (2021)

Corrigendum: Effect of the cPKCγ-Ng Signaling System on Rapid Eye Movement Sleep Deprivation-Induced Learning and Memory Impairment in Rats
por: Xu, Shu, et al.
Publicado: (2021)

BDNF-TrkB Signaling Coupled to nPKCε and cPKCβI Modulate the Phosphorylation of the Exocytotic Protein Munc18-1 During Synaptic Activity at the Neuromuscular Junction
por: Simó, Anna, et al.
Publicado: (2018)

cPKCγ‐mediated down‐regulation of UCHL1 alleviates ischaemic neuronal injuries by decreasing autophagy via ERK‐mTOR pathway
por: Zhang, Dan, et al.
Publicado: (2017)

ERK1/2 and p38 MAPKs Are Complementarily Involved in Estradiol 17ß-d-Glucuronide-Induced Cholestasis: Crosstalk with cPKC and PI3K
por: Boaglio, Andrea C., et al.
Publicado: (2012)

Host cell perforation by listeriolysin O (LLO) activates a Ca(2+)-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes Listeria monocytogenes internalization independently of membrane resealing
por: Lam, Jonathan G. T., et al.
Publicado: (2018)

Heterogeneity of white adipocytes in metabolic disease
por: Bilson, Josh, et al.
Publicado: (2023)

The Role of PKC-MAPK Signalling Pathways in the Development of Hyperglycemia-Induced Cardiovascular Complications
por: Jubaidi, Fatin Farhana, et al.
Publicado: (2022)

Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation
por: Liu, Mengling, et al.
Publicado: (2017)

An In Vitro Model to Probe the Regulation of Adipocyte Differentiation under Hyperglycemia
por: Shilpa, Kusampudi, et al.
Publicado: (2013)

PKC-ALDH2 Pathway Plays a Novel Role in Adipocyte Differentiation
por: Yu, Yu-Hsiang, et al.
Publicado: (2016)

Leptin reverses hyperglycemia and hyperphagia in insulin deficient diabetic rats by pituitary-independent central nervous system actions
por: da Silva, Alexandre A., et al.
Publicado: (2017)

Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling
por: Denroche, Heather C., et al.
Publicado: (2011)

PKCα diffusion and translocation are independent of an intact cytoskeleton
por: Hui, Xin, et al.
Publicado: (2017)

PKCα is required for Akt-mTORC1 activation in Non-Small Cell Lung Carcinoma (NSCLC) with EGFR mutation
por: Salama, Mohamed F., et al.
Publicado: (2019)

Hyperglycemia: An independent accompaniment of COVID -19
por: Goel, Anil Kumar, et al.
Publicado: (2021)

PKCε Stimulated Arginine Methylation of RIP140 for Its Nuclear-Cytoplasmic Export in Adipocyte Differentiation
por: Gupta, Pawan, et al.
Publicado: (2008)

Contraction stimulates muscle glucose uptake independent of atypical PKC
por: Yu, Haiyan, et al.
Publicado: (2015)

White fat, factitious hyperglycemia, and the role of FDG PET to enhance understanding of adipocyte metabolism
por: Hofman, Michael S, et al.
Publicado: (2011)

Biogenesis of P-TEFb in CD4(+) T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways
por: Mbonye, Uri, et al.
Publicado: (2021)

Telmisartan reverses antiretroviral-induced adipocyte toxicity and insulin resistance in vitro
por: Pushpakom, Sudeep P, et al.
Publicado: (2018)

Going Forward with Pokemon Go
por: Chong, Yvette, et al.
Publicado: (2018)

COVID-19, Hyperglycemia, and New-Onset Diabetes
por: Khunti, Kamlesh, et al.
Publicado: (2021)

PKCα and PKCδ: Friends and Rivals
por: Black, Jennifer D., et al.
Publicado: (2022)

Hyperglycemia-induced posterior reversible encephalopathy syndrome: A rare cause of reversible blindness
por: Dev, Nishanth, et al.
Publicado: (2019)

Hyperglycemia Affects miRNAs Expression Pattern during Adipogenesis of Human Visceral Adipocytes—Is Memorization Involved?
por: Strycharz, Justyna, et al.
Publicado: (2018)

Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis
por: Vorhagen, Susanne, et al.
Publicado: (2018)

Ubiquitylation in ERAD: Reversing to Go Forward?
por: Tsai, Yien Che, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_5kt8jpoutu7f9vv9pk6slu5hol