The Dwarf Phenotype in GH240B Mice, Haploinsufficient for the Autism Candidate Gene Neurobeachin, Is Caused by Ectopic Expression of Recombinant Human Growth Hormone

Two knockout mouse models for the autism candidate gene Neurobeachin (Nbea) have been generated independently. Although both models have similar phenotypes, one striking difference is the dwarf phenotype observed in the heterozygous configuration of the GH240B model that is generated by the serendip...

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Detalles Bibliográficos
Autores principales: Nuytens, Kim, Tuand, Krizia, Fu, Quili, Stijnen, Pieter, Pruniau, Vincent, Meulemans, Sandra, Vankelecom, Hugo, Creemers, John W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198124/
https://www.ncbi.nlm.nih.gov/pubmed/25333629
http://dx.doi.org/10.1371/journal.pone.0109598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198124/
https://www.ncbi.nlm.nih.gov/pubmed/25333629
http://dx.doi.org/10.1371/journal.pone.0109598

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