Potential Role for the Metnase Transposase Fusion Gene in Colon Cancer through the Regulation of Key Genes

The Metnase fusion gene consists of a SET histone methyltransferase domain and a transposase domain from Mariner transposase. This transposable element is involved in chromosome decatenation, enhances DNA repair, promotes foreign DNA integration, and assists topoisomerase II function. This study inv...

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Detalles Bibliográficos
Autores principales: Apostolou, Panagiotis, Toloudi, Maria, Kourtidou, Eleni, Mimikakou, Georgia, Vlachou, Ioanna, Chatziioannou, Marina, Kipourou, Vasiliki, Papasotiriou, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198141/
https://www.ncbi.nlm.nih.gov/pubmed/25333365
http://dx.doi.org/10.1371/journal.pone.0109741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198141/
https://www.ncbi.nlm.nih.gov/pubmed/25333365
http://dx.doi.org/10.1371/journal.pone.0109741

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