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Potential Role for the Metnase Transposase Fusion Gene in Colon Cancer through the Regulation of Key Genes
The Metnase fusion gene consists of a SET histone methyltransferase domain and a transposase domain from Mariner transposase. This transposable element is involved in chromosome decatenation, enhances DNA repair, promotes foreign DNA integration, and assists topoisomerase II function. This study inv...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198141/ https://www.ncbi.nlm.nih.gov/pubmed/25333365 http://dx.doi.org/10.1371/journal.pone.0109741 |