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Serial Low Doses of Sorafenib Enhance Therapeutic Efficacy of Adoptive T Cell Therapy in a Murine Model by Improving Tumor Microenvironment

Requirements of large numbers of transferred T cells and various immunosuppressive factors and cells in the tumor microenvironment limit the applications of adoptive T cells therapy (ACT) in clinic. Accumulating evidences show that chemotherapeutic drugs could act as immune supportive instead of imm...

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Detalles Bibliográficos
Autores principales: Chuang, Hui-Yen, Chang, Ya-Fang, Liu, Ren-Shyan, Hwang, Jeng-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198194/
https://www.ncbi.nlm.nih.gov/pubmed/25333973
http://dx.doi.org/10.1371/journal.pone.0109992