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Targeting the MET receptor tyrosine kinase in non-small cell lung cancer: emerging role of tivantinib

MET receptor tyrosine kinase and its natural ligand, hepatocyte growth factor, have been implicated in a variety of cancers, including non-small cell lung cancer (NSCLC). Mechanisms by which cellular deregulation of MET occurs include overexpression, genomic amplification, mutation, or alternative s...

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Detalles Bibliográficos
Autores principales: Agwa, Eberechi S, Ma, Patrick C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198276/
https://www.ncbi.nlm.nih.gov/pubmed/25328417
http://dx.doi.org/10.2147/CMAR.S37345