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Targeting the MET receptor tyrosine kinase in non-small cell lung cancer: emerging role of tivantinib
MET receptor tyrosine kinase and its natural ligand, hepatocyte growth factor, have been implicated in a variety of cancers, including non-small cell lung cancer (NSCLC). Mechanisms by which cellular deregulation of MET occurs include overexpression, genomic amplification, mutation, or alternative s...
Autores principales: | Agwa, Eberechi S, Ma, Patrick C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198276/ https://www.ncbi.nlm.nih.gov/pubmed/25328417 http://dx.doi.org/10.2147/CMAR.S37345 |
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