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Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers

BACKGROUND: Aberrant DNA methylation is a hallmark of many cancers. Classically there are two types of endometrial cancer, endometrioid adenocarcinoma (EAC), or Type I, and uterine papillary serous carcinoma (UPSC), or Type II. However, the whole genome DNA methylation changes in these two classical...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Xing, XiaoYun, Li, Jing, Lowdon, Rebecca F, Zhou, Yan, Lin, Nan, Zhang, Baoxue, Sundaram, Vasavi, Chiappinelli, Katherine B, Hagemann, Ian S, Mutch, David G, Goodfellow, Paul J, Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198682/
https://www.ncbi.nlm.nih.gov/pubmed/25286960
http://dx.doi.org/10.1186/1471-2164-15-868