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Essential Function for PDLIM2 in Cell Polarization in Three-Dimensional Cultures by Feedback Regulation of the β1-Integrin–RhoA Signaling Axis()()

PDLIM2 is a cytoskeletal and nuclear PDZ-LIM domain protein that regulates the stability of Nuclear Factor kappa-B (NFκB) and other transcription factors, and is required for polarized cell migration. PDLIM2 expression is suppressed by methylation in different cancers, but is strongly expressed in i...

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Detalles Bibliográficos
Autores principales: Deevi, Ravi Kiran, Cox, Orla T., O'Connor, Rosemary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198691/
https://www.ncbi.nlm.nih.gov/pubmed/24863845
http://dx.doi.org/10.1016/j.neo.2014.04.006