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4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression

BACKGROUND: 4-Methylumbelliferone (4-MU), a hyaluronan (HA) synthesis inhibitor, has antitumor activity in cancer cells. However, few studies have focused on its effects on ovarian cancer. The aim of this study was to investigate the effects of 4-MU on ovarian cancer and to elucidate its mechanism o...

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Detalles Bibliográficos
Autores principales: Tamura, Ryosuke, Yokoyama, Yoshihito, Yoshida, Hidemi, Imaizumi, Tadaatsu, Mizunuma, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198731/
https://www.ncbi.nlm.nih.gov/pubmed/25304388
http://dx.doi.org/10.1186/s13048-014-0094-2