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An Efficient Estimator of the Mutation Parameter and Analysis of Polymorphism from the 1000 Genomes Project
The mutation parameter θ is fundamental and ubiquitous in the analysis of population samples of DNA sequences. This paper presents a new highly efficient estimator of θ by utilizing the phylogenetic information among distinct alleles in a sample of DNA sequences. The new estimator, called Allelic BL...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198917/ https://www.ncbi.nlm.nih.gov/pubmed/25055200 http://dx.doi.org/10.3390/genes5030561 |