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Kainate receptor activation induces glycine receptor endocytosis through PKC deSUMOylation

Surface expression and regulated endocytosis of glycine receptors (GlyRs) play a critical function in balancing neuronal excitability. SUMOylation (SUMO modification) is of critical importance for maintaining neuronal function in the central nervous system. Here we show that activation of kainate re...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Lu, Li, Zuo, Yong, Wang, Yan, Jiao, Yingfu, Zeng, Wei-Zheng, Huang, Chao, Zhu, Michael X., Zamponi, Gerald W., Zhou, Tong, Xu, Tian-Le, Cheng, Jinke, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199113/
https://www.ncbi.nlm.nih.gov/pubmed/25236484
http://dx.doi.org/10.1038/ncomms5980