Runx1 is required for progression of CD41(+) embryonic precursors into HSCs but not prior to this

Haematopoiesis in adult animals is maintained by haematopoietic stem cells (HSCs), which self-renew and can give rise to all blood cell lineages. The AGM region is an important intra-embryonic site of HSC development and a wealth of evidence indicates that HSCs emerge from the endothelium of the emb...

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Detalles Bibliográficos
Autores principales: Liakhovitskaia, Anna, Rybtsov, Stanislav, Smith, Tom, Batsivari, Antoniana, Rybtsova, Natalia, Rode, Christina, de Bruijn, Marella, Buchholz, Frank, Gordon-Keylock, Sabrina, Zhao, Suling, Medvinsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199125/
https://www.ncbi.nlm.nih.gov/pubmed/25139854
http://dx.doi.org/10.1242/dev.110841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199125/
https://www.ncbi.nlm.nih.gov/pubmed/25139854
http://dx.doi.org/10.1242/dev.110841

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