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Runx1 is required for progression of CD41(+) embryonic precursors into HSCs but not prior to this

Haematopoiesis in adult animals is maintained by haematopoietic stem cells (HSCs), which self-renew and can give rise to all blood cell lineages. The AGM region is an important intra-embryonic site of HSC development and a wealth of evidence indicates that HSCs emerge from the endothelium of the emb...

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Detalles Bibliográficos
Autores principales:	Liakhovitskaia, Anna, Rybtsov, Stanislav, Smith, Tom, Batsivari, Antoniana, Rybtsova, Natalia, Rode, Christina, de Bruijn, Marella, Buchholz, Frank, Gordon-Keylock, Sabrina, Zhao, Suling, Medvinsky, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2014
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199125/ https://www.ncbi.nlm.nih.gov/pubmed/25139854 http://dx.doi.org/10.1242/dev.110841

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