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In vivo single-molecule imaging identifies altered dynamics of calcium channels in dystrophin-mutant C. elegans
Single-molecule (SM) fluorescence microscopy allows the imaging of biomolecules in cultured cells with a precision of a few nanometres but has yet to be implemented in living adult animals. Here we used split-GFP (green fluorescent protein) fusions and complementation-activated light microscopy (CAL...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199201/ https://www.ncbi.nlm.nih.gov/pubmed/25232639 http://dx.doi.org/10.1038/ncomms5974 |