DQB1*06:02-Associated Pathogenic Anti-Myelin Autoimmunity in Multiple Sclerosis-Like Disease: Potential Function of DQB1*06:02 as a Disease-Predisposing Allele

Susceptibility to multiple sclerosis (MS) has been linked mainly to the HLA-DRB1 locus, with the HLA-DR15 haplotype (DRB1*1501-DQA1*0102-DQB1*0602-DRB5*0101) dominating MS risk in Caucasians. Although genes in the HLA-II region, particularly DRB1*1501, DQA1*0102-DQB1*0602, are in tight linkage diseq...

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Detalles Bibliográficos
Autores principales: Kaushansky, Nathali, Ben-Nun, Avraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199271/
https://www.ncbi.nlm.nih.gov/pubmed/25360418
http://dx.doi.org/10.3389/fonc.2014.00280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199271/
https://www.ncbi.nlm.nih.gov/pubmed/25360418
http://dx.doi.org/10.3389/fonc.2014.00280

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