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Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate

Various histone modifications decorate nucleosomes within transcribed genes. Among these, monoubiquitylation of histone H2B (H2Bub1) and methylation of histone H3 on lysines 36 (H3K36me2/3) and 79 (H3K79me2/3) correlate positively with gene expression. By measuring the progression of the transcripti...

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Detalles Bibliográficos
Autores principales: Fuchs, Gilad, Hollander, Dror, Voichek, Yoav, Ast, Gil, Oren, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199367/
https://www.ncbi.nlm.nih.gov/pubmed/25049226
http://dx.doi.org/10.1101/gr.176487.114