Evolutionarily diverse determinants of meiotic DNA break and recombination landscapes across the genome

Fission yeast Rec12 (Spo11 homolog) initiates meiotic recombination by forming developmentally programmed DNA double-strand breaks (DSBs). DSB distributions influence patterns of heredity and genome evolution, but the basis of the highly nonrandom choice of Rec12 cleavage sites is poorly understood,...

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Detalles Bibliográficos
Autores principales: Fowler, Kyle R., Sasaki, Mariko, Milman, Neta, Keeney, Scott, Smith, Gerald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199369/
https://www.ncbi.nlm.nih.gov/pubmed/25024163
http://dx.doi.org/10.1101/gr.172122.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199369/
https://www.ncbi.nlm.nih.gov/pubmed/25024163
http://dx.doi.org/10.1101/gr.172122.114

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