OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines

The application of designer nucleases allows the induction of DNA double-strand breaks (DSBs) at user-defined genomic loci. Due to imperfect DNA repair mechanisms, DSBs can lead to alterations in the genomic architecture, such as the disruption of the reading frame of a critical exon. This can be ex...

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Detalles Bibliográficos
Autores principales: Schmid-Burgk, Jonathan L., Schmidt, Tobias, Gaidt, Moritz M., Pelka, Karin, Latz, Eicke, Ebert, Thomas S., Hornung, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199374/
https://www.ncbi.nlm.nih.gov/pubmed/25186908
http://dx.doi.org/10.1101/gr.176701.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199374/
https://www.ncbi.nlm.nih.gov/pubmed/25186908
http://dx.doi.org/10.1101/gr.176701.114

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