Induced growth inhibition, cell cycle arrest and apoptosis in CD133(+)/CD44(+) prostate cancer stem cells by flavopiridol

Flavopiridol is a flavone that inhibits several cyclin-dependent kinases and exhibits potent growth-inhibitory activity, apoptosis and G(1)-phase arrest in a number of human tumor cell lines. Flavopiridol is currently undergoing investigation in human clinical trials. The present study focused on th...

Descripción completa

Detalles Bibliográficos
Autores principales: SONER, BURAK CEM, AKTUG, HUSEYIN, ACIKGOZ, EDA, DUZAGAC, FAHRIYE, GUVEN, UMMU, AYLA, SULE, CAL, CAG, OKTEM, GULPERI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199402/
https://www.ncbi.nlm.nih.gov/pubmed/25216351
http://dx.doi.org/10.3892/ijmm.2014.1930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199402/
https://www.ncbi.nlm.nih.gov/pubmed/25216351
http://dx.doi.org/10.3892/ijmm.2014.1930

Ejemplares similares