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Induced growth inhibition, cell cycle arrest and apoptosis in CD133(+)/CD44(+) prostate cancer stem cells by flavopiridol
Flavopiridol is a flavone that inhibits several cyclin-dependent kinases and exhibits potent growth-inhibitory activity, apoptosis and G(1)-phase arrest in a number of human tumor cell lines. Flavopiridol is currently undergoing investigation in human clinical trials. The present study focused on th...
Autores principales: | SONER, BURAK CEM, AKTUG, HUSEYIN, ACIKGOZ, EDA, DUZAGAC, FAHRIYE, GUVEN, UMMU, AYLA, SULE, CAL, CAG, OKTEM, GULPERI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199402/ https://www.ncbi.nlm.nih.gov/pubmed/25216351 http://dx.doi.org/10.3892/ijmm.2014.1930 |
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