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HSP70 Promoter-Driven Activation of Gene Expression for Immunotherapy Using Gold Nanorods and Near Infrared Light

Modulation of the cytokine milieu is one approach for vaccine development. However, therapy with pro-inflammatory cytokines, such as IL-12, is limited in practice due to adverse systemic effects. Spatially-restricted gene expression circumvents this problem by enabling localized amplification. Intra...

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Detalles Bibliográficos
Autores principales: Andersson, Helen A., Kim, Yoo-Shin, O’Neill, Brian E., Shi, Zheng-Zheng, Serda, Rita E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199457/
https://www.ncbi.nlm.nih.gov/pubmed/25328682
http://dx.doi.org/10.3390/vaccines2020216