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Canonical Correlation Analysis for Gene-Based Pleiotropy Discovery

Genome-wide association studies have identified a wealth of genetic variants involved in complex traits and multifactorial diseases. There is now considerable interest in testing variants for association with multiple phenotypes (pleiotropy) and for testing multiple variants for association with a s...

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Detalles Bibliográficos
Autores principales: Seoane, Jose A., Campbell, Colin, Day, Ian N. M., Casas, Juan P., Gaunt, Tom R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199483/
https://www.ncbi.nlm.nih.gov/pubmed/25329069
http://dx.doi.org/10.1371/journal.pcbi.1003876