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The Vesicle Protein SAM-4 Regulates the Processivity of Synaptic Vesicle Transport

Axonal transport of synaptic vesicles (SVs) is a KIF1A/UNC-104 mediated process critical for synapse development and maintenance yet little is known of how SV transport is regulated. Using C. elegans as an in vivo model, we identified SAM-4 as a novel conserved vesicular component regulating SV tran...

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Detalles Bibliográficos
Autores principales: Zheng, Qun, Ahlawat, Shikha, Schaefer, Anneliese, Mahoney, Tim, Koushika, Sandhya P., Nonet, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199485/
https://www.ncbi.nlm.nih.gov/pubmed/25329901
http://dx.doi.org/10.1371/journal.pgen.1004644