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The Vesicle Protein SAM-4 Regulates the Processivity of Synaptic Vesicle Transport
Axonal transport of synaptic vesicles (SVs) is a KIF1A/UNC-104 mediated process critical for synapse development and maintenance yet little is known of how SV transport is regulated. Using C. elegans as an in vivo model, we identified SAM-4 as a novel conserved vesicular component regulating SV tran...
Autores principales: | Zheng, Qun, Ahlawat, Shikha, Schaefer, Anneliese, Mahoney, Tim, Koushika, Sandhya P., Nonet, Michael L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199485/ https://www.ncbi.nlm.nih.gov/pubmed/25329901 http://dx.doi.org/10.1371/journal.pgen.1004644 |
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