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Uncovering Enhancer Functions Using the α-Globin Locus

Over the last three decades, studies of the α- and β-globin genes clusters have led to elucidation of the general principles of mammalian gene regulation, such as RNA stability, termination of transcription, and, more importantly, the identification of remote regulatory elements. More recently, deta...

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Detalles Bibliográficos
Autor principal: Vernimmen, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199490/
https://www.ncbi.nlm.nih.gov/pubmed/25330308
http://dx.doi.org/10.1371/journal.pgen.1004668