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Uncovering Enhancer Functions Using the α-Globin Locus
Over the last three decades, studies of the α- and β-globin genes clusters have led to elucidation of the general principles of mammalian gene regulation, such as RNA stability, termination of transcription, and, more importantly, the identification of remote regulatory elements. More recently, deta...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199490/ https://www.ncbi.nlm.nih.gov/pubmed/25330308 http://dx.doi.org/10.1371/journal.pgen.1004668 |